The global total COVID-19 cases has crossed the historic number of 160.3 million mark (160,318,983)and the daily global COVID-19 cases are increasing and yesterday it has registered a higher single day spike of over 7.1 lakh (710,122) cases with the single day deaths of 13,444 with 17,958,123 active COVID-19 cases on 10.5.21 with the global recovery rate of 98% and the death rate of 2%.Among total the currently infected global COVID-19 cases 99.4% were in mild clinical condition and about 0.6% were in critical condition as on 11.5.2021USA COVID-19 cases are declining and it has registered a single day spike of over 34k (34,904) COVID-19 cases and the total cases has crossed 33.5 mllion mark (33,550,115) with over 5.9 lakh (596,946) total deaths ( single day deaths of 743 with 6,395,031 active COVID-19 cases on 11.5.21.Brazil becomes third in the global list on 11.5.2021 and the total COVID-19 cases were with 15,214,030 and 425,711 deaths with the single day spike of 71,018 new cases and 2,275 newer deaths with 1,012,146 active COVID-19 cases on 11.5.2021In India over 172.7 million (172,710,066) were vaccinated against COVID-19 as on 11.5.20210n 11.5.21 during the COVID-19 Pandemic India comes up to second place after USA in the global list of total COVID-19 cases and India becomes first in global single day cases with the higher number of 348,499 cases on 11.5.21Cases and death rate in India Tamilnadu and in Trichy are in raise again as second wave and India's higher single day spike of COVID-19 over 3.4 lakh (348,499) with the higher deaths of 4200 and the total has crossed 23.3 million mark (23,340,426) on 11.5.21 during this Pandemic. The recovered cases were second to U.S over 19.3 million mark (19,376,650) and the active COVID-19 cases are 3,709,551 as of 11.5.21.As of 12.5.21 in 220 countries ( Saint Helena is the 220th country added on 25.4.21 )and territories has recorded over 160.3 Million mark (160,323,352) cases with India over 23.3Million mark (23,340,426) with 29,272 new cases and the total crosses 1.4 million mark (1,438,509) with 162,181 active COVID-19 cases in the State of Tamilnadu , and in Trichy 879 new cases and the total crosses 31k (31,153) with 4882 active cases cases were reported with COVID-19 infection .Recovered cases were over 138 Million mark (138,058,378) and over 3.3 million mark (3,331,132) deaths in world which has crossed 2.5 lakh mark (254,224) in India and 298 (T 16,178) in Tamilnadu and 7(T 286 )at Trichy has been recorded as of 12.5.2021.M.A.Aleem Neurologist Trichy Tamilnadu India