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Coroners warn health secretary of clozapine deaths
BMJ 2018; 363 doi: https://doi.org/10.1136/bmj.k5421 (Published 27 December 2018)
Cite this as: BMJ 2018;363:k5421
Re: Coroners warn health secretary of clozapine deaths
Causes for death with Clozapine
Antipsychotic drug Clozapine can be associated with Myocarditis Cardiomyopathy Venous thrombosis Pulmonary embolism and Gsterointestinal motility disorders. All these can leads to sudden death in clozapine users. Myocarditis with in two to three weeks may be due to IgE immune mediated one . Venous thrombosis around three months can be due to hypercoagulabe state on venous side. Constipation may be due to slow peristaltic movement of the intestines.
Competing interests: No competing interests
06 January 2019
M.A. Aleem
Emeritus Professor of Neurology * Visiting Specialist in Neurology ** Consultant Neurologist ***
The Tamilnadu Dr.M.G.R. Medical University * Dhanalakshami Srinivasan Medical College ** ABC Hospital ***
Chennai 600032* Perambalure 621212** Trichy 620018*** Tamilnadu India
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