Wednesday, June 30, 2021
Tuesday, June 29, 2021
Neurology of COVID-19 Fatigue - M.A.Aleem BMJ 2021;373:n1610
BMJ British Medical Journal
Editor's Choice
How can we manage covid fatigue?
BMJ 2021; 373 doi: https://doi.org/10.1136/bmj.n1610 (Published 24 June 2021)
Cite this as: BMJ 2021;373:n1610
Re: How can we manage covid fatigue?
Dear Editor
Neurology of COVID-19 Fatigue
With COVID-19 infection, fatigue can present in the mild early stages, during the severe clinical condition and in the post COVID-19 period.
Fatigue is one of the most common (38% to 55%) symptoms in the early stage and it is most persistent and debilitating in many people with COVID-19 infection.
Fatigue can be due to central, psychological, and/or peripheral mechanisms due to the COVID-19.
Many factors can contribute to fatigue with Covid-19 infection, which include changes in neurotransmitter levels, inflammation, psychological disorders, stress levels, cognitive dysfunction, impaired oxygen delivery to the brain, and skeletal muscle involvment.
The central factors influencing COVID-19 fatigue may be a result of the virus invading the central nervous system directly. Other central factors which may also contribute to COVID-19 fatigue include changes in neurotransmitter levels (e.g., dopamine and serotonin), intrinsic neuronal excitability, demyelination (resulting in changes in axonal conduction velocity), and many others.
The recent functional neuroimaging studies in COVID-19 patients have also demonstrated frontal hypometabolism and cerebellar hypermetabolism, which may also have an impact on fatigue.
In the periphery, COVID-19 may directly impact the skeletal muscle and, therefore, contribute to fatigue.
Various skeletal muscle cell types may independently and/or collectively show vulnerability to COVID-19 via angiotensin-converting enzyme 2 (ACE2). COVID-19 in the lungs activates various leukocytes to release a cascade of cytokines, including interleukin-6 (IL-6). Notably, systemic elevations of IL-6 can also disrupt the muscle metabolic homeostasis and exacerbate the muscle loss and can cause fatigue.
Competing interests: No competing interests
26 June 2021
M.A. Aleem
Emeritus Professor of Neurology * Visiting Specialist in Neurology ** Consultant Neurologist ***
The Tamilnadu Dr.M.G.R. Medical University * Dhanalakshami Srinivasan Medical College ** ABC Hospital ***
Chennai 600032* Perambalure 621212** Trichy 620018*** Tamilnadu India
@drmaaleem
Monday, June 28, 2021
Ideal COVID-19 Vaccine for Indian International Travelers - M.A.Aleem Neurologist #Trichy #Tamilnadu #India
Ideal COVID-19 Vaccine for Indian International Travelers
- M.A.Aleem Neurologist #Trichy #Tamilnadu #India
The Government of India has approved three vaccines for use in India – Covishield (Oxford -AstraZeneca), Covaxin, and Sputnik.
Eligible Indians who have intention to travel abroad should produce their Passport as ID for COVID-19 vaccination purpose.
Out of the three vaccines approved for use in India, only one—Covishield—features on the emergency use listing (EUL) of the World Health Organization (WHO). This listing is significant because many countries are now using it as a benchmark for allowing vaccinated foreign nationals to travel.
At present Covishield ( Oxford- AstraZeneca ) COVID-19 vaccine has been approved in
43 Countries which includes
Afghanistan,
Antigua and Barbuda,
Argentina,Bahrain,Bangladesh,
Barbados,Bhutan,
Bolivia, (Plurinational State of)
Botswana,Brazil,Cabo Verde,
Canada,Côte d'Ivoire,Dominica,
Egypt,Ethiopia,Ghana,Grenada,
Hungary,India,Jamaica,
Lebanon,Maldives,Morocco,
Myanmar,
Namibia,Nepal,Nicaragua,
Nigeria,Saint Kitts and Nevis,
Saint Lucia,
Saint Vincent and the Grenadines,Seychelles,
Solomon Islands,Somalia,
South Africa,Sri Lanka,
Suriname,The Bahamas,
Togo,Tonga,
Trinidad and Tobago and
Ukraine.
Covaxin vaccine against COVID-19 is presently approved in 9 countries like
Guyana,India,
Iran (Islamic Republic of),
Mauritius,Mexico,Nepal,
Paraguay,Philippines and
Zimbabwe.
So at present
Indians travelling abroad are desperately trying to get Covishield jabs as that is the only vaccine recognised by most nations.
Sunday, June 27, 2021
Saturday, June 26, 2021
COVID-19 Cases Are Declining In India - M.A.Aleem #Neurologist #Trichy #Tamilnadu #India
COVID-19 Cases Are Declining In India - M.A.Aleem #Neurologist #Trichy #Tamilnadu #India
As of now on 19.06.2021
the global total COVID-19 cases has crossed the 178.6 million mark (178,659,524)
and the daily global COVID-19 cases and deaths are declining now.
On 18.06.2021 world has registered a single day spike of over 4 lakh (401,422) cases with the global single day deaths of 8,565 ( Total Global Death 3,866,795) with 11,616,550 active COVID-19 cases.
On 18.06.2021 the global recovery rate was 98% and the death rate was 2%.
At present among total the currently infected global COVID-19 cases, about 99.3% were mildly ill and 0.7% were in critical condition
At present (on 18.06.2021), India is in the second place after USA in the global list of total COVID-19 cases and it becomes second after Brazil in the world, in reporting the COVID-19 cases in a single day .
Because of our Prime Minister Modi 's vigilant efforts,
COVID-19 Cases and its death rate in India are declining now.
As of 18.06.2021,
India's single day spike of COVID-19 has come down around 60k (60,800) with the reduction in the single day COVID-19 related deaths .
In india as of 18.06.2021 the total COVID-19 cases has crossed 29.8 million mark (29,822,764)
during this Pandemic. The recovered cases were 28,670,878 and it is second to U.S. The present active COVID-19 cases are 766,718 in India
In COVID-19 vaccination drive with our Prime minister Modi's efforts
over 272.3 million (272,388,783) were vaccinated against COVID-19 in India as on 19.06.2021.
In the state of Tamilnadu with the constant efforts of our new chief minister M.K.Stalin, COVID-19 cases and its deaths are declining now in the second wave
In my home district of Trichy , the COVID-19 cases and the COVID-19 related deaths are now coming down in the second wave.
In COVID-19 vaccination drive my home district of Trichy is in the 6th place in the state of Tamilnadu as of 18.06.2021 with the total number of 4.1 lakh vaccinations against COVID-19.
Friday, June 25, 2021
Thursday, June 24, 2021
Wednesday, June 23, 2021
Tuesday, June 22, 2021
Monday, June 21, 2021
Sunday, June 20, 2021
For #COVID19Vaccination there no dietary restrictions including Non- Veg Says M.A.Aleem Neurologist #Trichy in Trichy The New Indian Express @NewIndianXpress article " Non-Veg Forwards Hits Turnout At Vax Camps" by @JayakumarMadala on 21.06.2021https://www.newindianexpress.com/states/tamil-nadu/2021/jun/21/non-veg-forwards-hit-weekend-turnout-at-vaccination-camps-in-tiruchy-2319316.html
Saturday, June 19, 2021
Friday, June 18, 2021
Pro, anti-NEET groups busy mobilising opinion- by Sampath Kumar in Trichy Times of India on 19.06.2021
Pro, anti-NEET groups busy mobilising opinion
...
Trichy: While the state government has appointed a committee headed by a retired high court judge to assess the impact of NEET on medical admission in the state, people from different walks of life have started raising their voice for and against the entrance test in social media and public forums. The committee had circulated an e-mail id (neetimpact2021@gmail.com) to seek opinion which has been widely shared by both sections.
It is a false narrative that NEET will improve the quality of medical education and the deserving will get seat, says Su Moorthy, member of Kalvi Mempattu Kootamaippu, an education rights organisation. He said only the elite can become a doctor as they can clear NEET by getting expensive coaching. The policy to increase the financial burden of parents by way of NEET coaching cannot be justified. Since Tamil Nadu has more medical colleges to offer more seats, other states are not opposing as their children too are getting an opportunity in Tamil Nadu, he said.
“We are not against students from other states becoming doctors. But we have a large rural population,” said M A Aleem, senior neurologist. “They will be treated effectively for ailments if one among them becomes doctor. For treating people in his village by becoming a doctor, why should he compete with students from across the country,” he said. Aleem said the state has the highest gross enrolment ratio in the country as we could give opportunity to them to pursue higher education. But opportunity must be given to prove themselves instead of denying seats to potential candidates through NEET.
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Social activist N Veerasekaran said a screening test is essential for professional courses like MBBS. While questions are asked from classes VII-XII syllabus, state board syllabus too has been upgraded. Last year most of the questions were asked from state board text books, he said. If rural students aren’t able to compete will urban students, then we need to improve the curriculum and enhance the capabilities of the teachers. There is no difference in the salary of government school teachers in urban and rural areas, he said.
However, S Jawahar, a parent of an MBBS student who cleared NEET, said earlier it was possible for the rich to get their children admitted to medical colleges even if they scored average marks in class XII. That is not possible now.
In 2010 November 11 K.N. Nehru as Transport minister inaugurated the Swine flu vaccination in our Trichy and that time in short duration swine flu is controlled . Like that this time on 17.6.2021 after 11 years K.N.Nehru as Municipal minister inaugurated the COVID vaccination for differently abled person at Trichy . so soon we will overcome and control COVID-19 in Trichy as in 2010 for swine flu - M.A.Aleem Neurologist Trichy Tamilnadu India
Thursday, June 17, 2021
Monday, June 14, 2021
Sunday, June 13, 2021
Thursday, June 10, 2021
Wednesday, June 9, 2021
Tuesday, June 8, 2021
Monday, June 7, 2021
Crowds back on streets as shops open in Tiruchi - The Hindu Tiruchi on 08.06.2021
https://www.thehindu.com/news/cities/Tiruchirapalli/crowds-back-on-streets-as-shops-reopen-in-tiruchi/article34753269.ece
The Hindu Tiruchi 08.06.2021
TIRUCHIRAPALLI
Crowds back on streets as shops open in Tiruchi
Crowds throng shops on Big Bazaar Street in Tiruchi on Monday. | Photo Credit: M. Moorthy
Special Correspondent
07 JUNE 2021 18:06 IST
UPDATED: 07 JUNE 2021 20:05 IST
TIRUCHI
Most of the stand alone shops and provisions stores opened on Monday in Tiruchi and some neighbouring districts following relaxation in lockdown restrictions.
Big crowds could be seen on the roads in Tiruchi, especially in commercial areas such as Big Bazaar Street, West Boulevard Road, Madurai Road, Thillai Nagar and Chathram Bus Stand area. In some places, there were even traffic snarls right through the day.
Apart from fruits and vegetable shops, groceries, hardware stores, electrical goods, book and stationery shops, cycle and two-wheeler repair shops opened as they were allowed to function from 6 a.m. to 5 p.m.
Although Gandhi Market remained closed, wholesale and retail vegetable shops were allowed to function on West Boulevard Road through the night and till the early hours of the day. A temporary fish market became functional at Central Bus Stand.
Commenting on the situation, M.A. Aleem, former Vice-Principal, K.A.P. Viswanatham Government Medical College, emphasised the need for people to maintain social distance, wear face masks properly and avoid visiting crowded places.
“The effectiveness of the lockdown will be determined only by the behaviour of the people. It is essential that people follow personal distance. Although more number of people have taken to wearing face masks, many can be seen wearing them improperly, either below their nose or chin,” Dr. Aleem observed.
People should not entertain negative thoughts or apprehensions about COVID 19, but, at the same time, those with symptoms should not hesitate to undergo testing immediately and follow medical advice, he added.
But for a few minor changes, most of the lockdown restrictions continued in Karur, Thanjavur, Tiruvarur, Nagapattinam and Mayiladuthurai districts in the central region where “the spread of COVID-19 had not come under control.”
